This formula provides a combination of nutrients that combat age-related fat accumulation. Fat cells (adipocytes) secrete a hormone called leptin that tells our brain we have eaten enough. Leptin can also facilitate the breakdown of stored triglycerides in our adipocytes via the process of lipolysis. Heavy individuals have startlingly high blood levels of leptin, indicating that their cells have become resistant to the leptin that is supposed to prevent them from putting on so many fat pounds. In a recent published study, Irvingia demonstrated a marked reduction in leptin blood levels, a reduction in appetite, followed by significant loss of body weight and inches off the waistline. Integra-Lean Irvingia: • Enhances resting energy expenditure at the cellular level • Impedes dietary fat absorption from the intestines • Slows intestinal carbohydrate absorption • Reduces hunger • Helps restore insulin sensitivity • Reduces the amount of blood glucose that is converted to stored fat (triglyceride) in the cells In a recent study of 102 overweight adults, who were given 150 mg of Irvingia twice daily and the control group was given a placebo for 10 weeks. The adults taking Irvingia lost 28 pounds and 6.4 inches from their waistlines while the placebo group lost 1.5 pounds and 2.1 inches from their waistlines